Postdoctoral Position in Cell Biology (F/M) (F/M)
75005, Paris, France
Working environment and context
Our institution is part of PSL University. Located in the heart of Paris, it brings together all areas of knowledge, innovation and creation. Ranked among the top 50 universities in the world, it trains researchers, artists, engineers, entrepreneurs and managers who are aware of their social, individual and collective responsibility in the field of research.
Hosting structure
The Curie Institute Research Center
The Institut Curie is a major player in the research and fight against cancer. It consists of a hospital and a Research Center of more than 1000 employees with a strong international representativeness. The objective of the Curie Institute Research Center is to develop basic research and to use the knowledge produced to improve the diagnosis, prognosis, and therapeutics of cancers as part of the continuum between basic research and innovation serving the patient.
Missions
Main tasks
Laboratory
The host laboratory, Membrane Mechanics and Dynamics of Intracellular Signaling, led by Dr Christophe Lamaze is part of the Chemical Biology of Cancer (UMR3666 CNRS-U1339 INSERM). The team research focuses on understanding how plasma membrane dynamics and trafficking control the signal transduction, in particular during mechanical stress. In the lab, Dr Cedric Blouin has developed an original line of research combining biochemistry and biophysics to investigate mechanobiology and lipid nanodomains in JAK/STAT signaling.
https://institut-curie.org/team/lamaze#presentation
The project
The interplay between plasma membrane lipids, membrane associated proteins, the actin cytoskeleton and dynamic scaffolding structures such as clathrin-coated assemblies and caveolae is still poorly understood. Deciphering how the dynamics and the nanoscale organization of the plasma membrane control cell signaling remains a major challenge in cell biology. Based on our previous work (Blouin et al. Cell 2016; Li et al. BioRxiv; Mani et al., Nat Cell Biol 2026), the project aims to determine how the IFN-γR signaling receptor dynamically interacts with lipid nanodomains at the plasma membrane, how it connects with the various molecular assemblies beneath, and how these interactions are tuned by mechanical cues. To elucidate the molecular mechanisms that control IFN-γR signaling, we will a unique combination of advanced imaging techniques upon control of membrane architecture and mechanical status. Building on recent C. Blouin’s ANR grant, the project will benefit from a well-equipped and strongly supported research environment, providing excellent conditions for ambitious research and will additionally involve French academic partners.
Applicant profile
Knowkedge and qualifications expected
Training and Skills required
- PhD in cell biology or biophysics with publications in these fields
- Scientific skills : prior experience in advanced microscopy, membrane biology, 3D model systems will be preferred. Knowledge in surface and matrix functionalization would be appreciated
- Professional experience desirable : up to four year after PhD
- Language skills : strong communication skills in English
Abiliites
- Strong motivation and ability to work independently, creativity and interest in interdisciplinary research
- Aptitude for working and integrating in a team
- Ability to communicate
- High level of integrity and rigor
All our opportunities are open to people with disabilities
Contract information
Type of contract: Fixed-term contract.
Starting date: early January at the latest
Duration: 2 years
Working time: full time
Remuneration: 3018.26 €/month, according to the current grids
Benefits: Collective catering, reimbursement of transportation fees up to 70%, supplementary health insurance
Location of the position: Paris
Contact
Please send your CV, letter of motivation and 2 references:
Publication date: 16/09/2026
Deadline for application: end of September
Faithful to the legacy of its founder, the Institut Curie is deeply committed to promoting equal opportunities, diversity, and inclusion. Convinced that diversity of backgrounds and experiences contributes to collective performance, we strive to provide everyone with a respectful and equitable working environment and encourage all candidates to apply for our job opportunities.
https://euraxess.ec.europa.eu/sites/default/files/brochures/eur_21620_en-fr.pdf
Diplôme et expérience professionnelle
Bac+6 et plusNon discrimination, openness and transparency
Our institution, like PSL University as a whole, is committed to supporting and promoting equality, diversity and inclusion within its communities. We encourage applications from a variety of backgrounds, which we will ensure are selected through an open and transparent recruitment process.
Contact
r67nf8fa315k@emploi.beetween.com
Other information
Postdoctoral Position in Cell Biology (F/M) (F/M)
| Location 75005, Paris, France |
|---|
| School Institut Curie |
Working environment and context
Notre établissement fait partie de l'Université PSL. Située au cœur de Paris, celle-ci fait dialoguer tous les domaines du savoir, de l'innovation et de la création. Classée parmi les 50 premières universités mondiales, elle forme au plus près de la recherche des chercheurs, artistes, ingénieurs, entrepreneurs ou dirigeants conscients de leur responsabilité sociale, individuelle et collective.
Hosting structure
The Curie Institute Research Center
The Institut Curie is a major player in the research and fight against cancer. It consists of a hospital and a Research Center of more than 1000 employees with a strong international representativeness. The objective of the Curie Institute Research Center is to develop basic research and to use the knowledge produced to improve the diagnosis, prognosis, and therapeutics of cancers as part of the continuum between basic research and innovation serving the patient.
Missions
Main tasks
Laboratory
The host laboratory, Membrane Mechanics and Dynamics of Intracellular Signaling, led by Dr Christophe Lamaze is part of the Chemical Biology of Cancer (UMR3666 CNRS-U1339 INSERM). The team research focuses on understanding how plasma membrane dynamics and trafficking control the signal transduction, in particular during mechanical stress. In the lab, Dr Cedric Blouin has developed an original line of research combining biochemistry and biophysics to investigate mechanobiology and lipid nanodomains in JAK/STAT signaling.
https://institut-curie.org/team/lamaze#presentation
The project
The interplay between plasma membrane lipids, membrane associated proteins, the actin cytoskeleton and dynamic scaffolding structures such as clathrin-coated assemblies and caveolae is still poorly understood. Deciphering how the dynamics and the nanoscale organization of the plasma membrane control cell signaling remains a major challenge in cell biology. Based on our previous work (Blouin et al. Cell 2016; Li et al. BioRxiv; Mani et al., Nat Cell Biol 2026), the project aims to determine how the IFN-γR signaling receptor dynamically interacts with lipid nanodomains at the plasma membrane, how it connects with the various molecular assemblies beneath, and how these interactions are tuned by mechanical cues. To elucidate the molecular mechanisms that control IFN-γR signaling, we will a unique combination of advanced imaging techniques upon control of membrane architecture and mechanical status. Building on recent C. Blouin’s ANR grant, the project will benefit from a well-equipped and strongly supported research environment, providing excellent conditions for ambitious research and will additionally involve French academic partners.
Applicant profile
Knowkedge and qualifications expected
Training and Skills required
- PhD in cell biology or biophysics with publications in these fields
- Scientific skills : prior experience in advanced microscopy, membrane biology, 3D model systems will be preferred. Knowledge in surface and matrix functionalization would be appreciated
- Professional experience desirable : up to four year after PhD
- Language skills : strong communication skills in English
Abiliites
- Strong motivation and ability to work independently, creativity and interest in interdisciplinary research
- Aptitude for working and integrating in a team
- Ability to communicate
- High level of integrity and rigor
All our opportunities are open to people with disabilities
Contract information
Type of contract: Fixed-term contract.
Starting date: early January at the latest
Duration: 2 years
Working time: full time
Remuneration: 3018.26 €/month, according to the current grids
Benefits: Collective catering, reimbursement of transportation fees up to 70%, supplementary health insurance
Location of the position: Paris
Contact
Please send your CV, letter of motivation and 2 references:
Publication date: 16/09/2026
Deadline for application: end of September
Faithful to the legacy of its founder, the Institut Curie is deeply committed to promoting equal opportunities, diversity, and inclusion. Convinced that diversity of backgrounds and experiences contributes to collective performance, we strive to provide everyone with a respectful and equitable working environment and encourage all candidates to apply for our job opportunities.
https://euraxess.ec.europa.eu/sites/default/files/brochures/eur_21620_en-fr.pdf
Diplôme et expérience professionnelle
Bac+6 et plusNon discrimination, ouverture et transparence
Notre établissement, comme l'ensemble de l'Université PSL, s’engage à soutenir et promouvoir l’égalité, la diversité et l’inclusion au sein de ses communautés. Nous encourageons les candidatures issues de profils variés, que nous veillerons à sélectionner via un processus de recrutement ouvert et transparent.
Contact
r67nf8fa315k@emploi.beetween.com
Other information
| Reference r67nf8fa31 |
|---|
Université PSL (Paris Sciences & Lettres)
