Postdoctoral Position in Epigenetics and Pediatric Oncology (F/M) (F/H)
75005, Paris, France
Environnement et contexte de travail
Notre établissement fait partie de l'Université PSL. Située au cœur de Paris, celle-ci fait dialoguer tous les domaines du savoir, de l'innovation et de la création. Classée parmi les 50 premières universités mondiales, elle forme au plus près de la recherche des chercheurs, artistes, ingénieurs, entrepreneurs ou dirigeants conscients de leur responsabilité sociale, individuelle et collective.
Structure d'accueil
The Curie Institute Research Center
The Institut Curie is a major player in research and fight against cancer. It consists of a hospital and a Research Center of more than 1000 employees with a strong international representativeness.
The objective of the Curie Institute Research Center is to develop basic research and to use the knowledge produced to improve the diagnosis, prognosis, and therapeutics of cancers as part of the continuum between basic research and innovation serving the patient.
Missions
Activités principales
At the Paris campus of the Institute Curie, the Translational Research in Pediatric Oncology (RTOP; Head: Dr. G. Schleiermacher) team of INSERM Unit 1330 (CONCERT; Director: Olivier Ayrault) develops methods for analyzing molecules isolated from peripheral samples (circulating cell-free DNA, cell-free RNAs, proteins) in large cohorts of patients with high-risk pediatric cancers (neuroblastoma, other high-risk cancers) in order to study mechanisms of oncogenesis and treatment resistance.
We are currently recruiting a postdoctoral researcher whose mission will be to develop approaches for studying methylation in patients with neuroblastoma, to contribute to improving the diagnosis and management of these patients, as well as our understanding of tumor development and metastatic dissemination. The candidate will work in an interdisciplinary environment involving next-generation sequencing methods, molecular tool development, and cell biology/screening applications, using both commercial and in-house solutions.
Essential duties and responsibilities
· Analysis of methylome dysregulation at the tumor level and in circulating DNA in neuroblastoma, to identify tumor subgroups and to analyze the role of divergent profiles in treatment resistance.
· Promoting the study of genetic and epigenetic alterations, and DNA-protein interactions, based on the development of new approaches to liquid biopsy analysis (NGS, WES, ChipSeq, exosomes, and other techniques) in neuroblastoma.
· Interface with the team's bioinformaticians for data analysis and interpretation.
Profil du candidat
Savoirs et compétences attendus
· Ph.D. in Molecular Biology, Chemistry, Biochemistry, or Biomedical Engineering with experience in technology development supported either by publications or patents (1-3 years).
· Hands-on experience with genomics technologies essential (i.e. qPCR, digital PCR, etc).
· Experience with NGS and data management a definite plus.
· Broad-knowledge of standard cell biology, DNA and RNA molecular biology techniques required.
· Desire to not only answer biological questions, but to innovate technology.
· Ability to work in a matrix environment sharing many tasks with the team and to rapidly evolve to meet changing needs.
· Ability to conduct research independently, work in a multidisciplinary environment, and collaborate nationally and internationally.
All our opportunities are open to people with disabilities
Contract information
Type of contract: CDD
Starting date: As soon as possible
Duration: 18 months renewable
Working time: 39 h
Remuneration: according to the current grids
Benefits: Collective catering, reimbursement of transportation fees up to 70%, supplementary health insurance
Location of the position: Paris
Contact
Please send your CV, letter of motivation and 2 references
Publication date: 29/01/2026
Deadline for application: until filled
Institut Curie is an inclusive, equal opportunity employer
and is dedicated to the highest standards of research integrity.
https://euraxess.ec.europa.eu/sites/default/files/brochures/eur_21620_en-fr.pdf
Diplôme et expérience professionnelle
Bac+6 et plusNon discrimination, ouverture et transparence
Notre établissement, comme l'ensemble de l'Université PSL, s’engage à soutenir et promouvoir l’égalité, la diversité et l’inclusion au sein de ses communautés. Nous encourageons les candidatures issues de profils variés, que nous veillerons à sélectionner via un processus de recrutement ouvert et transparent.
Contact
xtxdf2jh0j5k@emploi.beetween.com
Autres informations
Postdoctoral Position in Epigenetics and Pediatric Oncology (F/M) (F/H)
| Localisation du poste 75005, Paris, France |
|---|
| Établissement Institut Curie |
Environnement et contexte de travail
Notre établissement fait partie de l'Université PSL. Située au cœur de Paris, celle-ci fait dialoguer tous les domaines du savoir, de l'innovation et de la création. Classée parmi les 50 premières universités mondiales, elle forme au plus près de la recherche des chercheurs, artistes, ingénieurs, entrepreneurs ou dirigeants conscients de leur responsabilité sociale, individuelle et collective.
Structure d'accueil
The Curie Institute Research Center
The Institut Curie is a major player in research and fight against cancer. It consists of a hospital and a Research Center of more than 1000 employees with a strong international representativeness.
The objective of the Curie Institute Research Center is to develop basic research and to use the knowledge produced to improve the diagnosis, prognosis, and therapeutics of cancers as part of the continuum between basic research and innovation serving the patient.
Missions
Activités principales
At the Paris campus of the Institute Curie, the Translational Research in Pediatric Oncology (RTOP; Head: Dr. G. Schleiermacher) team of INSERM Unit 1330 (CONCERT; Director: Olivier Ayrault) develops methods for analyzing molecules isolated from peripheral samples (circulating cell-free DNA, cell-free RNAs, proteins) in large cohorts of patients with high-risk pediatric cancers (neuroblastoma, other high-risk cancers) in order to study mechanisms of oncogenesis and treatment resistance.
We are currently recruiting a postdoctoral researcher whose mission will be to develop approaches for studying methylation in patients with neuroblastoma, to contribute to improving the diagnosis and management of these patients, as well as our understanding of tumor development and metastatic dissemination. The candidate will work in an interdisciplinary environment involving next-generation sequencing methods, molecular tool development, and cell biology/screening applications, using both commercial and in-house solutions.
Essential duties and responsibilities
· Analysis of methylome dysregulation at the tumor level and in circulating DNA in neuroblastoma, to identify tumor subgroups and to analyze the role of divergent profiles in treatment resistance.
· Promoting the study of genetic and epigenetic alterations, and DNA-protein interactions, based on the development of new approaches to liquid biopsy analysis (NGS, WES, ChipSeq, exosomes, and other techniques) in neuroblastoma.
· Interface with the team's bioinformaticians for data analysis and interpretation.
Profil du candidat
Savoirs et compétences attendus
· Ph.D. in Molecular Biology, Chemistry, Biochemistry, or Biomedical Engineering with experience in technology development supported either by publications or patents (1-3 years).
· Hands-on experience with genomics technologies essential (i.e. qPCR, digital PCR, etc).
· Experience with NGS and data management a definite plus.
· Broad-knowledge of standard cell biology, DNA and RNA molecular biology techniques required.
· Desire to not only answer biological questions, but to innovate technology.
· Ability to work in a matrix environment sharing many tasks with the team and to rapidly evolve to meet changing needs.
· Ability to conduct research independently, work in a multidisciplinary environment, and collaborate nationally and internationally.
All our opportunities are open to people with disabilities
Contract information
Type of contract: CDD
Starting date: As soon as possible
Duration: 18 months renewable
Working time: 39 h
Remuneration: according to the current grids
Benefits: Collective catering, reimbursement of transportation fees up to 70%, supplementary health insurance
Location of the position: Paris
Contact
Please send your CV, letter of motivation and 2 references
Publication date: 29/01/2026
Deadline for application: until filled
Institut Curie is an inclusive, equal opportunity employer
and is dedicated to the highest standards of research integrity.
https://euraxess.ec.europa.eu/sites/default/files/brochures/eur_21620_en-fr.pdf
Diplôme et expérience professionnelle
Bac+6 et plusNon discrimination, ouverture et transparence
Notre établissement, comme l'ensemble de l'Université PSL, s’engage à soutenir et promouvoir l’égalité, la diversité et l’inclusion au sein de ses communautés. Nous encourageons les candidatures issues de profils variés, que nous veillerons à sélectionner via un processus de recrutement ouvert et transparent.
Contact
xtxdf2jh0j5k@emploi.beetween.com
Autres informations
| Référence xtxdf2jh0j |
|---|
L'Université PSL (Paris Sciences & Lettres)
