Study Engineer (F/M) (F/H)
75005, Paris, France
Environnement et contexte de travail
Notre établissement fait partie de l'Université PSL. Située au cœur de Paris, celle-ci fait dialoguer tous les domaines du savoir, de l'innovation et de la création. Classée parmi les 50 premières universités mondiales, elle forme au plus près de la recherche des chercheurs, artistes, ingénieurs, entrepreneurs ou dirigeants conscients de leur responsabilité sociale, individuelle et collective.
Structure d'accueil
Le Centre de recherche de l’Institut Curie
Premier centre français de recherche et de lutte contre le cancer, l'Institut Curie associe un centre de recherche de renommée internationale et un hôpital de pointe. Il offre un environnement d’excellence, où les expertises se mêlent autour de valeurs communes : bienveillance, humanité, ouverture, partage, efficacité, innovation, solidarité et engagement.
Missions
Activités principales
Team “Mechanisms of Repression by Polycomb Group Proteins”
Our research team aims to understand the principles that govern gene regulation by the highly conserved family of chromatin modifiers known as Polycomb proteins, from the biochemical to the cellular and organismal levels. We are affiliated with the Institut Curie Research Center’s Genetics and Developmental Biology Unit (Inserm U934/CNRS UMR3215).
https://institut-curie.org/team/margueron
Missions
- Perform CRISPR-based genetic screens coupled to single cell transcriptomics.
- Engineer various stem cell models (iPS, ES) by genome editing and characterize their transcriptomic and epigenomic properties.
- Conduct biochemical studies of novel Polycomb-associated proteins.
- Participate in all common tasks such as equipment maintenance, renewing stocks, student training, etc.
Activities
- Cloning
- Library preparation (RNA-seq, CUT&RUN-seq, etc.)
- Protein expression and purification, protein pulldowns, Western blot
- Maintenance and differentiation of various stem/progenitor cells
- Lentiviral transduction, transfection
- FACS sorting
- Proliferation and differentiation assays
- Interpretation, synthesis and reporting of results
Constraints and risks
- Biosafety level 2 laboratory
- Routine chemical risks
Profil du candidat
Savoirs et compétences attendus
Training and experience required
- Master’s degree in life sciences or equivalent
- Expertise in molecular biology (cloning, PCR, RNA purification, protein purification)
- Expertise in cell culture
- Knowledge of or experience in CRISPR-based methods and/or single-cell RNA-seq
Skills required
- Rigor and scientific integrity
- Ability to work independently
- Perseverance and team spirit
Contract information
Type of contract: Fixed-term contract
Starting date: December 2026-January 2027
Duration: 18 months; renewable once
Working time: Full time (218 days/year)
Annual Gross Salary : from 29240 € to 33013 € according to the current grids
Benefits: Institute cafeteria, reimbursement of transportation fees up to 70%, supplementary health insurance
Location of the position: Paris
Contact
Please send your CV, letter of motivation and 2 references
Publication date: 21/10/2026
Deadline for application: Once filled
Faithful to the legacy of its founder, the Institut Curie is deeply committed to promoting equal opportunities, diversity, and inclusion. Convinced that diversity of backgrounds and experiences contributes to collective performance, we strive to provide everyone with a respectful and equitable working environment and encourage all candidates to apply for our job opportunities.All our opportunities are open to people with disabilities
https://euraxess.ec.europa.eu/sites/default/files/brochures/eur_21620_en-fr.pdf
Diplôme et expérience professionnelle
Bac+5Non discrimination, ouverture et transparence
Notre établissement, comme l'ensemble de l'Université PSL, s’engage à soutenir et promouvoir l’égalité, la diversité et l’inclusion au sein de ses communautés. Nous encourageons les candidatures issues de profils variés, que nous veillerons à sélectionner via un processus de recrutement ouvert et transparent.
Contact
dx08qf1w245k@emploi.beetween.com
Autres informations
Study Engineer (F/M) (F/H)
| Poste à pourvoirle 01/12/2026 | Localisation du poste 75005, Paris, France |
|---|---|
| Établissement Institut Curie |
Environnement et contexte de travail
Notre établissement fait partie de l'Université PSL. Située au cœur de Paris, celle-ci fait dialoguer tous les domaines du savoir, de l'innovation et de la création. Classée parmi les 50 premières universités mondiales, elle forme au plus près de la recherche des chercheurs, artistes, ingénieurs, entrepreneurs ou dirigeants conscients de leur responsabilité sociale, individuelle et collective.
Structure d'accueil
Le Centre de recherche de l’Institut Curie
Premier centre français de recherche et de lutte contre le cancer, l'Institut Curie associe un centre de recherche de renommée internationale et un hôpital de pointe. Il offre un environnement d’excellence, où les expertises se mêlent autour de valeurs communes : bienveillance, humanité, ouverture, partage, efficacité, innovation, solidarité et engagement.
Missions
Activités principales
Team “Mechanisms of Repression by Polycomb Group Proteins”
Our research team aims to understand the principles that govern gene regulation by the highly conserved family of chromatin modifiers known as Polycomb proteins, from the biochemical to the cellular and organismal levels. We are affiliated with the Institut Curie Research Center’s Genetics and Developmental Biology Unit (Inserm U934/CNRS UMR3215).
https://institut-curie.org/team/margueron
Missions
- Perform CRISPR-based genetic screens coupled to single cell transcriptomics.
- Engineer various stem cell models (iPS, ES) by genome editing and characterize their transcriptomic and epigenomic properties.
- Conduct biochemical studies of novel Polycomb-associated proteins.
- Participate in all common tasks such as equipment maintenance, renewing stocks, student training, etc.
Activities
- Cloning
- Library preparation (RNA-seq, CUT&RUN-seq, etc.)
- Protein expression and purification, protein pulldowns, Western blot
- Maintenance and differentiation of various stem/progenitor cells
- Lentiviral transduction, transfection
- FACS sorting
- Proliferation and differentiation assays
- Interpretation, synthesis and reporting of results
Constraints and risks
- Biosafety level 2 laboratory
- Routine chemical risks
Profil du candidat
Savoirs et compétences attendus
Training and experience required
- Master’s degree in life sciences or equivalent
- Expertise in molecular biology (cloning, PCR, RNA purification, protein purification)
- Expertise in cell culture
- Knowledge of or experience in CRISPR-based methods and/or single-cell RNA-seq
Skills required
- Rigor and scientific integrity
- Ability to work independently
- Perseverance and team spirit
Contract information
Type of contract: Fixed-term contract
Starting date: December 2026-January 2027
Duration: 18 months; renewable once
Working time: Full time (218 days/year)
Annual Gross Salary : from 29240 € to 33013 € according to the current grids
Benefits: Institute cafeteria, reimbursement of transportation fees up to 70%, supplementary health insurance
Location of the position: Paris
Contact
Please send your CV, letter of motivation and 2 references
Publication date: 21/10/2026
Deadline for application: Once filled
Faithful to the legacy of its founder, the Institut Curie is deeply committed to promoting equal opportunities, diversity, and inclusion. Convinced that diversity of backgrounds and experiences contributes to collective performance, we strive to provide everyone with a respectful and equitable working environment and encourage all candidates to apply for our job opportunities.All our opportunities are open to people with disabilities
https://euraxess.ec.europa.eu/sites/default/files/brochures/eur_21620_en-fr.pdf
Diplôme et expérience professionnelle
Bac+5Non discrimination, ouverture et transparence
Notre établissement, comme l'ensemble de l'Université PSL, s’engage à soutenir et promouvoir l’égalité, la diversité et l’inclusion au sein de ses communautés. Nous encourageons les candidatures issues de profils variés, que nous veillerons à sélectionner via un processus de recrutement ouvert et transparent.
Contact
dx08qf1w245k@emploi.beetween.com
Autres informations
| Référence dx08qf1w24 |
|---|
L'Université PSL (Paris Sciences & Lettres)
