Post-Doc position in Molecular Biology Droplet-based microfluidics and RNA expression CBI - ESPCIParis LBC Team - Pr Andrew Griffiths (F/H)
10 Rue Vauquelin 75005 Paris
Environnement et contexte de travail
Notre établissement fait partie de l'Université PSL. Située au cœur de Paris, celle-ci fait dialoguer tous les domaines du savoir, de l'innovation et de la création. Classée parmi les 50 premières universités mondiales, elle forme au plus près de la recherche des chercheurs, artistes, ingénieurs, entrepreneurs ou dirigeants conscients de leur responsabilité sociale, individuelle et collective.
Structure d'accueil
ESPCI Paris - PSL
ESPCI Paris - PSLis a major institution of higher education (a French "Grande Écoled’ingénieurs"), an internationally renowned research center (6 Nobel Prizes), and a fertile ground of innovation for industry (3 start-ups created/year). ESPCI is a highly multidisciplinary environment with teaching and research in physics, chemistry and biology.
Prof. Andrew Griffiths’ Lab
The research activities of the Laboratory of Biochemistry team at ESPCI Paris-PSL, directed by Prof. Andrew GRIFFITHS, are based around droplet-based microfluidics, a powerful new ultrahigh-throughput system in which reaction volumes can be miniaturized by up to a million-fold compared to conventional assays in microtitre plates. This opens up exciting prospects for the development of extremely innovative systems with many applications in the Life Sciences. The successful candidate will join a highly multidisciplinary team, with experience spanning biology, chemistry and physics.
Mission
Informations - Recherche
CBI - ESPCIParis-PSL LBC Team - Prof. Andrew Griffiths
Project
The dynamic nature of chromatin and transcriptional features are expected to participate to tumor evolution, particularly in the context of response to cancer treatment and acquisition of resistance. In triple-negative breast cancer (TNBC), we have recently revealed the heterogeneity of chromatin states in patient-derived xenografts models of acquired resistance to Capecitabine.
The Post-Doc will work on the development of droplet-based microfluidics approach for the simultaneous profiling of histone modifications and RNA expression on the very same cell.
Compétences attendues
Requirements
We are seeking a highly motivated Post-Docwith strong experience in molecular biology(scChIP-seq and RNA-seq) or related field. Experience in microfluidics, cell biology and bioinformatics are very appreciated.
Flexibility, autonomy, the ability to work in a highly multidisciplinary team and good interpersonal skills are essential.
Non discrimination, ouverture et transparence
Notre établissement, comme l'ensemble de l'Université PSL, s’engage à soutenir et promouvoir l’égalité, la diversité et l’inclusion au sein de ses communautés. Nous encourageons les candidatures issues de profils variés, que nous veillerons à sélectionner via un processus de recrutement ouvert et transparent.
Modalités de candidature
Address your applications(CV + cover letter) by email to:
Prof. Andrew GRIFFITHS
ESPCI Paris–LBC Team
10 Rue Vauquelin - 75005 Paris
Contact
Andrew
Prof. GRIFFITHS
job-lbc@espci.fr
Accès
ESPCI Paris–LBC Team
10 Rue Vauquelin - 75005 Paris
Metro line 7 station Censier daubenton, Bus 21,27
Autres informations
Post-Doc position in Molecular Biology Droplet-based microfluidics and RNA expression CBI - ESPCIParis LBC Team - Pr Andrew Griffiths (F/H)
| Poste à pourvoir Starting date :February2021 | Localisation du poste 10 Rue Vauquelin 75005 Paris |
|---|---|
| Établissement ESPCI Paris - PSL |
Environnement et contexte de travail
Notre établissement fait partie de l'Université PSL. Située au cœur de Paris, celle-ci fait dialoguer tous les domaines du savoir, de l'innovation et de la création. Classée parmi les 50 premières universités mondiales, elle forme au plus près de la recherche des chercheurs, artistes, ingénieurs, entrepreneurs ou dirigeants conscients de leur responsabilité sociale, individuelle et collective.
Structure d'accueil
ESPCI Paris - PSL
ESPCI Paris - PSLis a major institution of higher education (a French "Grande Écoled’ingénieurs"), an internationally renowned research center (6 Nobel Prizes), and a fertile ground of innovation for industry (3 start-ups created/year). ESPCI is a highly multidisciplinary environment with teaching and research in physics, chemistry and biology.
Prof. Andrew Griffiths’ Lab
The research activities of the Laboratory of Biochemistry team at ESPCI Paris-PSL, directed by Prof. Andrew GRIFFITHS, are based around droplet-based microfluidics, a powerful new ultrahigh-throughput system in which reaction volumes can be miniaturized by up to a million-fold compared to conventional assays in microtitre plates. This opens up exciting prospects for the development of extremely innovative systems with many applications in the Life Sciences. The successful candidate will join a highly multidisciplinary team, with experience spanning biology, chemistry and physics.
Mission d'enseignement
Mission de recherche
CBI - ESPCIParis-PSL LBC Team - Prof. Andrew Griffiths
Project
The dynamic nature of chromatin and transcriptional features are expected to participate to tumor evolution, particularly in the context of response to cancer treatment and acquisition of resistance. In triple-negative breast cancer (TNBC), we have recently revealed the heterogeneity of chromatin states in patient-derived xenografts models of acquired resistance to Capecitabine.
The Post-Doc will work on the development of droplet-based microfluidics approach for the simultaneous profiling of histone modifications and RNA expression on the very same cell.
Compétences attendues
Requirements
We are seeking a highly motivated Post-Docwith strong experience in molecular biology(scChIP-seq and RNA-seq) or related field. Experience in microfluidics, cell biology and bioinformatics are very appreciated.
Flexibility, autonomy, the ability to work in a highly multidisciplinary team and good interpersonal skills are essential.
Non discrimination, ouverture et transparence
Notre établissement, comme l'ensemble de l'Université PSL, s’engage à soutenir et promouvoir l’égalité, la diversité et l’inclusion au sein de ses communautés. Nous encourageons les candidatures issues de profils variés, que nous veillerons à sélectionner via un processus de recrutement ouvert et transparent.
Modalités de candidature
Address your applications(CV + cover letter) by email to:
Prof. Andrew GRIFFITHS
ESPCI Paris–LBC Team
10 Rue Vauquelin - 75005 Paris
Contact
Andrew Prof. GRIFFITHSjob-lbc@espci.fr
Accès
ESPCI Paris–LBC Team
10 Rue Vauquelin - 75005 Paris
Metro line 7 station Censier daubenton, Bus 21,27
Autres informations
| Expérience souhaitée
Niveau doctorant (R1) an |
Référence 13313 |
|---|
L'Université PSL (Paris Sciences & Lettres)
